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    Nonalcoholic Fatty Liver Disease (NAFLD)

    Nonalcoholic fatty liver disease is diagnosed from a liver biopsy showing moderate to gross macroves...

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    Amyloidosis

    Amyloidosis is a medical condition resulting from aggregation of extracellularly deposited abnormal ...

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    Intracellular Accumulations

    Intracellular accumulations include the following: 1. Water (hydropic change) 2. Fatty change:...

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    Cellular Aging

    Cellular death due to aging is caused by accumulation of injurious events and genetically controlled...

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    Types of Necrosis

    Necrosis may be coagulative, liquifactive, caseous, fat necrosis, gummatous necrosis or fibrinoid ne...

Markers of Bone Turn Over

Osteoclast

Bone is constantly undergoing formation & resorption (remodeling) with the two processes occurring in equal amounts. Markers with increased bone ... Read More »

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Causes of Osteomalacia

Osteoclast

The causes of osteomalacia may be grouped into vitamin disorders, calcium deficiency, phosphate deficiency, disorders of bone matrix and inhibitors ... Read More »

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Osteopenia and Osteoporosis

osteoporosis

Major Classification of Osteopenia Osteoporosis Osteogenesis imperfecta Osteomalacia Malignancy Osteitis fibrosa Classification of osteoporosis 1. Senile 8. Genetic disorders 2. ... Read More »

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Causes of Hyperparathyroidism and Hypoparathyroidism

parathyroid

Hyperparathyroidism Hyperparathyroidism may be primary or secondary. 1. Primary hyperparathyroidism a. Sporadic Causes · Solitary adenoma (commonest) · Cheif ... Read More »

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Causes of Hypocalcemia and Hypercalcemia

calcium

Causes of Hypocalcemia 1. Artifact (low serum albumin; rapid volume expansion) 2. Hypoparathyroidism 3. Pseudohypoparathyroidism 4. Postoperative resection of parathyroid ... Read More »

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Introduction to Body Calcium and Vitamin D

Calcium Calcium is a major constituent of bone and hence an important structural element in the body. Plasma Calcium The ... Read More »

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Hypoglycemia and its Causes

A working definition of clinical hypoglycaemia is a low blood glucose level less than 3.0 mmol/l, associated with characteristic, but ... Read More »

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Diagnostic Criteria and Complications of Diabetes Mellitus

Diabetes is diagnosed if: a. HbA1C ≥ 6.5%, OR b. Fasting plasma glucose (FPG) ≥ 126 mg/dl (7.0 mmol/l), OR c. ... Read More »

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Classification of Diabetes Mellitus

WHO Definition of Diabetes Mellitus A state of chronic hyperglycaemia which may result from genetic or environmental factors often acting ... Read More »

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Causes of Hyperglycemia

Fasting blood glucose level higher than 126 mg/dl or 7.0 mmol/l is labeled as hyperglycemia. Fasting hyperglycaemia may occur in ... Read More »

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